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A rare cytogenetic presentation of acute myeloid leukemia (AML-M2).

Acta medica Iranica - 1 Jan 2012

Kumari Prasanna, LingappaKavitha Bidadi, Obula Reddy Chintaparthi, Mangalagowri Maiana, Madhumathi Danem Satienariana, Mahadeva Prasad Madaiah, Raghavendra Hanumanthappa Vijay, Premalata Chennagiri Shinivasa Murthy, Lakshmaiah Kuntejowdahalli Channaviriappa, Mir Mazloumi Seyed Hashem

Abstract excerpt

Acute myeloid leukemia (AML) with t(8;21)(q22;q22) generating the AML1/ETO fusion gene on 8q22 is a distinct type of AML t(8;21) category (WHO)/AML-M2 (FAB), generally associated with a favourable prognosis. Variant additional chromosomal abnormalities are frequently reported. We report three adult cases of this category with unusual karyotype. Bone marrow cytogenetics of case no. 1: 45,X,-Y, t(8;21)(q13;q22)...

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PMID: 23456526

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