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Article

Genetic approaches to study Legionella pneumophila pathogenicity.

FEMS microbiology reviews - 1 Jun 1994

Ott M

Abstract excerpt

Legionella pneumophila is an intracellular pathogen replicating in human macrophages during the course of infection of the lungs. Infection by legionellae often leads to severe pneumonia, termed Legionnaires' disease. Genetic approaches to identify the factors responsible for L. pneumophila pathogenicity started with the construction of genomic libraries in Escherichia coli. Various L. pneumophila-specific genes...

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PMID: 8049098
DOI: 10.1111/j.1574-6976.1994.tb00085.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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