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Article

UHG crossmatching. A comparison with PCR-SSO typing in the selection of HLA-DPB1-compatible bone marrow donors.

Transplantation - 27 Jul 1994

Clay T M, Culpan D, Howell W M, Sage D A, Bradley B A, Bidwell J L

Abstract excerpt

The technique of universal heteroduplex generator (UHG) crossmatching has been developed to permit comparison of HLA-DPB1 alleles between two or more individuals. It offers a rapid and simple method of screening prospective bone marrow donors for HLA-DPB1 compatibility with the recipient. We present the nucleotide sequence and describe the method of construction of the DPB1 UHG. To test its effectiveness, 56...

Topics

Alleles
Base Sequence
Bone Marrow Transplantation
HLA-DP Antigens
HLA-DP beta-Chains
Histocompatibility Testing
Humans
Molecular Sequence Data
Nucleic Acid Heteroduplexes
Oligonucleotides
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tissue Donors

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Identifiers

PMID: 8042239

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8042239-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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