Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Induction of cell cycle progression by hepatitis B virus HBx gene expression in quiescent mouse fibroblasts.

1 Jul 1994

Abstract excerpt

The HBx gene of hepatitis B virus has been shown to induce hepatic tumors in transgenic mice and is implicated in hepatocarcinogenesis in human hepatitis B virus infection. To further characterize the role of HBx gene in carcinogenesis, we established mouse fibroblast cell lines in which the expression of HBx gene could be controlled by glucocorticoid hormone and examined the effect of HBx gene expression on cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to RNA Interference and Gene Delivery
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8040286
DOI: 10.1172/jci117343

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction of cell cycle progression by hepatitis B virus HBx gene expression in quiescent mouse fibroblasts.PMID 8040286Read ↗

Stimulation of Cellular Proliferation by Hepatitis B Virus X ProteinSemantic proximity Read ↗

Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls.Semantic proximity Read ↗

The Hepatitis B Virus X Protein Modulates Hepatocyte Proliferation Pathways To Stimulate Viral ReplicationSemantic proximity Read ↗

Role and Functional Domain of Hepatitis B Virus X Protein in Regulating HBV Transcription and Replication in Vitro and in VivoSemantic proximity Read ↗

Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx.Semantic proximity Read ↗

The hepatitis B virus X gene induces p53-mediated programmed cell deathSemantic proximity Read ↗

Regulation of transforming growth factor-beta 1 expression by the hepatitis B virus (HBV) X transactivator. Role in HBV pathogenesis.Semantic proximity Read ↗

Induction of apoptosis after switch-on of the hepatitis B virus X gene mediated by the Cre/loxP recombination systemSemantic proximity Read ↗

Glucocorticoid Stimulates Hepatitis B Viral Gene Expression in Cultured Human Hepatoma CellsSemantic proximity Read ↗

Hepatoma-derived integrated HBV DNA causes multi-stage transformation in vitro.Semantic proximity Read ↗

Hepatitis B virus transactivator X protein is not tumorigenic in transgenic miceSemantic proximity Read ↗

Expression of Hepatitis B Virus X Protein Does Not Alter the Accumulation of Spontaneous Mutations in Transgenic MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.