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Article

Stimulation of Cellular Proliferation by Hepatitis B Virus X Protein

1 Jan 2001

Abstract excerpt

Chronic infection with the hepatitis B virus (HBV) is a known risk factor in the development of human hepatocellular carcinoma (HCC). The HBV-encoded X protein, HBx, has been investigated for properties that may explain its cancer cofactor role in transgenic mouse lines. We discuss here recent data showing that HBx is able to induce hepatocellular proliferation in vitro and in vivo. This property of HBx is...

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Identifiers

PMID: 11790880
DOI: 10.1155/2001/571254

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