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Induction of apoptosis after switch-on of the hepatitis B virus X gene mediated by the Cre/loxP recombination system

1 Dec 1999

Abstract excerpt

The HBx protein of hepatitis B virus is a multifunctional protein that is implicated in the pathogenesis of hepatocellular carcinoma by regulating gene transcription, causing cell proliferation and, as shown recently, inducing cell death. However, analysis of the effects of HBx in stable cultured cell clones has been hampered because only cell lines that adapted to the effects of HBx were selected during the...

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PMID: 10567659
DOI: 10.1099/0022-1317-80-12-3257

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Induction of apoptosis after switch-on of the hepatitis B virus X gene mediated by the Cre/loxP recombination systemPMID 10567659Read ↗

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