Article
The cdc7 protein kinase is a dosage dependent regulator of septum formation in fission yeast.
The EMBO journal - 1 Jul 1994
Fankhauser C, Simanis V
Abstract excerpt
Mutation of the Schizosaccharomyces pombe cdc7 gene prevents formation of the division septum and cytokinesis. We have cloned the cdc7 gene and show that it encodes a protein kinase which is essential for cell division. In the absence of cdc7 function, spore germination, DNA synthesis and mitosis are unaffected, but cells are unable to initiate formation of the division septum. Overexpression of p120cdc7 causes...
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