Article
Interpreting the effects of site-directed mutagenesis on active transport systems.
Biochimica et biophysica acta - 13 Jul 1994
Krupka R M
Abstract excerpt
Single amino acid substitutions in the lactose permease of Escherichia coli are known to elicit behaviour, such as the transformation of an active into a passive system, not explained by current co-transport models. The behaviour, it is shown, can be explained by an expanded reaction scheme that takes account of the required alternation of the carrier, in the course of the coupled reaction, between mobile and...
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