Article
CD8+ T cell profiles in patients with rheumatoid arthritis and their relationship to disease activity.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Feb 2015
Carvalheiro Helena, Duarte Cátia, Silva-Cardoso Sandra, da Silva José A P, Souto-Carneiro M Margarida
Abstract excerpt
OBJECTIVE: CD8+ T cells are abundant in rheumatoid arthritis (RA). However, their role in disease pathogenesis is poorly defined. This study was undertaken to investigate the relationship between disease activity and CD8+ T cell phenotypes, production of cytokines, and production of cytotoxic molecules in the peripheral blood (PB) and synovial fluid (SF) of patients with RA. METHODS: CD8+ T cell phenotypes were...
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