Mutagenic specificity of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the supF shuttle vector system.

Article

Mutagenic specificity of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the supF shuttle vector system.

Cancer research - 15 Jul 1994

Endo H, Schut H A, Snyderwine E G

Abstract excerpt

2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) are heterocyclic amine mutagens/carcinogens formed from the cooking of meat. Here we used the pSP189 shuttle vector developed by Parris and Seidman (Gene, 117: 1-5, 1992) to study and compare t...

Topics

Base Sequence
Cell Line
DNA
Genes, Suppressor
Genetic Vectors
Humans
Imidazoles
Molecular Sequence Data
Mutagens
Mutation
Plasmids
Quinolines

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