Article
Distribution of the DNA adducts of 2-amino-3-methylimidazo[4,5-f] quinoline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the supF gene as determined by polymerase arrest assay.
Molecular carcinogenesis - 1 Nov 1995
Endo H, Schut H A, Snyderwine E G
Abstract excerpt
The distribution of the adducts of the cooked meat-derived heterocyclic amines 2-amino-3-methylimidazo[4,5-f] quinoline (IQ) and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhlP) was examined in the supF gene of PSP189 by a polymerase-arrest assay using thermal-cycle sequencing. The reactive...
Topics
- Autoradiography
- Base Sequence
- Binding Sites
- DNA Adducts
- DNA-Directed DNA Polymerase
- Genes, Suppressor
- Imidazoles
- Molecular Sequence Data
- Mutagens
- Mutation
- Quinolines
- RNA, Transfer