Gene expression during skeletal development in three osteopetrotic rat mutations. Evidence for osteoblast abnormalities.

Article

Gene expression during skeletal development in three osteopetrotic rat mutations. Evidence for osteoblast abnormalities.

The Journal of biological chemistry - 25 May 1991

Shalhoub V, Jackson M E, Lian J B, Stein G S, Marks S C

Abstract excerpt

Osteopetrosis is a group of metabolic bone diseases characterized by reductions in osteoclast development and/or function. These aspects of osteoclast biology are known to be influenced by osteoblasts and their products. To ascertain whether osteoblast dysfunction contributes to aberrations in th...

Topics

Animals
Autoradiography
Body Weight
Bone and Bones
Extracellular Matrix
Gene Expression Regulation
Mutation
Osteoblasts
Osteopetrosis
RNA, Messenger
Rats

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