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Article

Adrenalectomy prevents behavioural sensitisation of mice to cocaine in a genotype-dependent manner.

Behavioural brain research - 27 Feb 2007

de Jong Inge E M, Oitzl Melly S, de Kloet E Ronald

Abstract excerpt

The objective of the present study was to investigate the contribution of adrenal stress hormones to strain differences in cocaine sensitivity. For this purpose, we have studied sensitisation to the locomotor stimulant effect of cocaine and, in parallel, cocaine-induced corticosterone secretion in two inbred mouse strains: C57BL/6 and DBA/2. Adrenalectomy ('ADX': surgical removal of the adrenal glands) was...

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Source

Identifiers

PMID: 17150264
DOI: 10.1016/j.bbr.2006.11.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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