Article
Differential requirements for segment polarity genes in wingless signaling.
Mechanisms of development - 1 Jun 1995
Noordermeer J, Klingensmith J, Nusse R
Abstract excerpt
The segment polarity genes wingless and engrailed are required throughout development of Drosophila. During early embryogenesis, these two genes are expressed in adjacent domains, in an inter-dependent way. Later, their expression is regulated by different mechanisms and becomes maintained by auto-regulation. To dissect the genetic requirements for the initial signaling between wingless and engrailed expressing...
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