Article
Differential requirements for segment polarity genes in wingless signaling.
Mechanisms of development - 1 Jun 1995
Noordermeer J, Klingensmith J, Nusse R
Abstract excerpt
The segment polarity genes wingless and engrailed are required throughout development of Drosophila. During early embryogenesis, these two genes are expressed in adjacent domains, in an inter-dependent way. Later, their expression is regulated by different mechanisms and becomes maintained by auto-regulation. To dissect the genetic requirements for the initial signaling between wingless and engrailed expressing...
Topics
- Animals
- Animals, Genetically Modified
- Drosophila
- Female
- Gene Expression Regulation, Developmental
- Genes, Insect
- Male
- Mutation
- RNA
- Signal Transduction
- Wings, Animal