Article
Absence of APP713 mutation in Italian and Russian families with schizophrenia.
Neuroscience letters - 3 Jan 1994
Mortilla M, Amaducci L, Bruni A, Montesi M P, Trubnikov A, De Cataldo S, Pallanti S, Pazzagli A, Grecu L, Servi P
Abstract excerpt
A recent study has shown a mutation at codon 713 of the amyloid precursor protein (APP) gene in a schizophrenic patient. We have analyzed the MaeIII restriction site caused by that mutation in Italian and Russian families with schizophrenia. No mutations were observed suggesting that the APP713 mutation is unlikely to be linked to the pathogenesis of such a psychiatric disorder.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.