Article
Absence of APP713 mutation in Italian and Russian families with schizophrenia.
Neuroscience letters - 3 Jan 1994
Mortilla M, Amaducci L, Bruni A, Montesi M P, Trubnikov A, De Cataldo S, Pallanti S, Pazzagli A, Grecu L, Servi P
Abstract excerpt
A recent study has shown a mutation at codon 713 of the amyloid precursor protein (APP) gene in a schizophrenic patient. We have analyzed the MaeIII restriction site caused by that mutation in Italian and Russian families with schizophrenia. No mutations were observed suggesting that the APP713 m...
Topics
- Alzheimer Disease
- Amyloid beta-Protein Precursor
- Base Sequence
- DNA
- Humans
- Italy
- Molecular Sequence Data
- Mutation
- Nervous System Diseases
- Polymerase Chain Reaction
- Restriction Mapping
- Russia
- Schizophrenia