Screening schizophrenic patients for mutations in the amyloid precursor protein gene.

Abstract excerpt

A limited number of rare missense mutations in exons 16 and 17 of the amyloid precursor protein (APP) gene have been reported. They are associated with a variety of phenotypes including cerebral haemorrhage, multi-infarct dementia and Alzheimer's disease. We recently reported an alanine to valine...

Topics

• Amyloid beta-Protein Precursor
• Base Sequence
• Exons
• Genetic Testing
• Humans
• Molecular Sequence Data
• Mutation
• Polymerase Chain Reaction
• Schizophrenia