Article
An eye-specific G beta subunit essential for termination of the phototransduction cascade.
Nature - 7 Jul 1994
Dolph P J, Man-Son-Hing H, Yarfitz S, Colley N J, Deer J R, Spencer M, Hurley J B, Zuker C S
Abstract excerpt
Heterotrimeric G proteins couple various receptors to intracellular effector molecules. Although the role of the G alpha subunit in effector activation, guanine nucleotide exchange and GTP hydrolysis has been well studied, the cellular functions of the G beta subunits are less well understood. G beta gamma dimers bind G alpha subunits and anchor them to the membrane for presentation to the receptor. In specific...
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