Serum modulation of the effects of TCDD on the in vitro antibody response and on enzyme induction in primary hepatocytes.

doi:10.1016/0162-3109(94)90044-2

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Article

Serum modulation of the effects of TCDD on the in vitro antibody response and on enzyme induction in primary hepatocytes.

Immunopharmacology - 1 Jan 2000

Morris D L, Jeong H G, Stevens W D, Chun Y J, Karras J G, Holsapple M P

Abstract excerpt

We have recently reported that the effects of TCDD on the in vitro antibody response can vary considerably depending on the serum conditions used in the culture media. To further investigate this phenomenon, studies were performed to compare the effects of TCDD on both splenocyte antibody respons...

Topics

Animals
Antibody Formation
Blood
Cells, Cultured
Culture Media
Cytochrome P-450 CYP1A1
Cytochrome P-450 Enzyme System
Enzyme Induction
Female
Genotype
Liver
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Mice, Inbred DBA
Oxidoreductases
Polychlorinated Dibenzodioxins
Receptors, Aryl Hydrocarbon

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PMID: 8014031
DOI: 10.1016/0162-3109(94)90044-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8014031-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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