Article
Serum modulation of the effects of TCDD on the in vitro antibody response and on enzyme induction in primary hepatocytes.
Immunopharmacology - 1 Jan 2000
Morris D L, Jeong H G, Stevens W D, Chun Y J, Karras J G, Holsapple M P
Abstract excerpt
We have recently reported that the effects of TCDD on the in vitro antibody response can vary considerably depending on the serum conditions used in the culture media. To further investigate this phenomenon, studies were performed to compare the effects of TCDD on both splenocyte antibody responses and P450 enzyme induction (EROD) in primary hepatocytes (HPTC) derived from B6C3F1 and DBA/2 mice when evaluated in...
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