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Article

Antibodies as a probe in cytochrome P450 research.

Drug metabolism and disposition: the biological fate of chemicals - 1 May 2009

Shou Magang, Lu Anthony Y H

Abstract excerpt

Cytochrome P450 (P450) is the superfamily of enzymes responsible for biotransformation of endobiotics and xenobiotics. However, their large isoform multiplicity, inducibility, diverse structure, widespread distribution, polymorphic expression, and broad overlapping substrate specificity make it difficult to measure the precise role of each individual P450 to the metabolism of drugs (or carcinogens) and hamper the...

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PMID: 19196844
DOI: 10.1124/dmd.108.025718

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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