Article
A 79 amino acid oncogene is responsible for human cytomegalovirus mtrII induced malignant transformation.
Archives of virology - 1 Jan 1994
Thompson J, Doniger J, Rosenthal L J
Abstract excerpt
Human cytomegalovirus (HCMV) morphological transforming region (mtr)II is the only HCMV mtr that was retained and expressed in transformed mouse or rat cells. The minimal transforming region has previously been shown to be within a 980-bp BanII/XhoI subfragment which encodes three open reading fr...
Topics
- 3T3 Cells
- Animals
- Base Sequence
- Cell Transformation, Neoplastic
- Cell Transformation, Viral
- Cloning, Molecular
- Cytomegalovirus
- DNA, Viral
- Genes, Viral
- Mice
- Mice, Nude
- Molecular Sequence Data
- Neoplasms, Experimental
- Oncogene Proteins
- Oncogene Proteins, Viral
- Oncogenes
- Open Reading Frames
- Phenotype