Article
UL69 of human cytomegalovirus, an open reading frame with homology to ICP27 of herpes simplex virus, encodes a transactivator of gene expression.
Journal of virology - 1 Jun 1994
Winkler M, Rice S A, Stamminger T
Abstract excerpt
The UL69 open reading frame of human cytomegalovirus (HCMV) is homologous to the immediate-early protein ICP27 of herpes simplex virus, an essential viral regulatory protein involved in the transition from early to late gene expression. Genes with homology to ICP27 have been detected in all subcl...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cells, Cultured
- Cytomegalovirus
- DNA, Viral
- Gene Expression Regulation, Viral
- Genes, Viral
- Genetic Complementation Test
- Herpesvirus 1, Human
- Humans
- Immediate-Early Proteins
- Molecular Sequence Data
- Mutation
- Open Reading Frames
- Sequence Homology, Amino Acid
- Trans-Activators
- Viral Proteins