Article
Pleiotropic effects of a Yersinia pestis fur mutation.
Journal of bacteriology - 1 Dec 1994
Staggs T M, Fetherston J D, Perry R D
Abstract excerpt
A Yersinia pestis fur mutation was constructed by insertionally disrupting the fur open reading frame. Analysis of a Fur-regulated beta-galactosidase reporter gene revealed a loss of iron regulation as a result of the fur mutation. trans complementation with the cloned Y. pestis fur gene restored iron regulation. The expression of most iron-regulated proteins was also deregulated by this mutation; however, a...
Topics
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Bacteriocins
- Gene Expression Regulation, Bacterial
- Genes, Reporter
- Hemin
- Iron
- Microbial Sensitivity Tests
- Mutagenesis, Insertional
- Mutation
- Phenotype