Article
Ferric Uptake Regulator Fur Is Conditionally Essential in Pseudomonas aeruginosa.
Journal of bacteriology - 15 Nov 2017
Pasqua Martina, Visaggio Daniela, Lo Sciuto Alessandra, Genah Shirley, Banin Ehud, Visca Paolo, Imperi Francesco
Abstract excerpt
In Pseudomonas aeruginosa, the ferric uptake regulator (Fur) protein controls both metabolism and virulence in response to iron availability. Differently from other bacteria, attempts to obtain fur deletion mutants of P. aeruginosa failed, leading to the assumption that Fur is an essential protein in this bacterium. By investigating a P. aeruginosa conditional fur mutant, we demonstrate that Fur is not essential...
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