Molecular cloning, iron-regulation and mutagenesis of the irp2 gene encoding HMWP2, a protein specific for the highly pathogenic Yersinia.

doi:10.1111/j.1365-2958.1992.tb01481.x

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Article

Molecular cloning, iron-regulation and mutagenesis of the irp2 gene encoding HMWP2, a protein specific for the highly pathogenic Yersinia.

Molecular microbiology - 1 Feb 1992

Carniel E, Guiyoule A, Guilvout I, Mercereau-Puijalon O

Abstract excerpt

Under iron-starvation, the highly pathogenic Yersinia synthesize several iron-regulated proteins including two high-molecular-weight polypeptides (HMWP1 and HMWP2). From the chromosome of Yersinia enterocolitica serovar O:8 (strain Ye 8081), the genes coding for the HMWP2 (irp2) and its promoter...

Topics

Animals
Bacterial Outer Membrane Proteins
Bacterial Proteins
Blotting, Southern
Cloning, Molecular
Electrophoresis, Polyacrylamide Gel
Escherichia coli
Female
Iron
Iron-Binding Proteins
Mice
Mutagenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Periplasmic Binding Proteins

Phenotype

Promoter Regions, Genetic

Restriction Mapping

Virulence

Yersinia enterocolitica

Source

Open in PubMed

Identifiers

PMID: 1552851
DOI: 10.1111/j.1365-2958.1992.tb01481.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1552851-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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