Article
Ribonuclease E provides substrates for ribonuclease P-dependent processing of a polycistronic mRNA.
Genes & development - 15 Dec 1994
Alifano P, Rivellini F, Piscitelli C, Arraiano C M, Bruni C B, Carlomagno M S
Abstract excerpt
The polycistronic mRNA of the histidine operon is subject to a processing event that generates a rather stable transcript encompassing the five distal cistrons. The molecular mechanisms by which such a transcript is produced were investigated in Escherichia coli strains carrying mutations in several genes for exo- and endonucleases. The experimental approach made use of S1 nuclease protection assays on in vivo...
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