Ribonuclease E provides substrates for ribonuclease P-dependent processing of a polycistronic mRNA.

doi:10.1101/gad.8.24.3021

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Article

Ribonuclease E provides substrates for ribonuclease P-dependent processing of a polycistronic mRNA.

Genes & development - 15 Dec 1994

Alifano P, Rivellini F, Piscitelli C, Arraiano C M, Bruni C B, Carlomagno M S

Abstract excerpt

The polycistronic mRNA of the histidine operon is subject to a processing event that generates a rather stable transcript encompassing the five distal cistrons. The molecular mechanisms by which such a transcript is produced were investigated in Escherichia coli strains carrying mutations in several genes for exo- and endonucleases. The experimental approach made use of S1 nuclease protection assays on in vivo...

Topics

Amino Acid Sequence
Bacterial Proteins
Base Sequence
Endoribonucleases
Escherichia coli
Escherichia coli Proteins
Gene Expression
Genes, Bacterial
Genotype
Histidine
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multienzyme Complexes

Nucleic Acid Conformation

Operon

Protein Biosynthesis

RNA Processing, Post-Transcriptional

RNA, Catalytic

RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 8001821
DOI: 10.1101/gad.8.24.3021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8001821-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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