Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural requirements for the processing of Escherichia coli 5 S ribosomal RNA by RNase E in vitro.

Journal of molecular biology - 20 Dec 1992

Cormack R S, Mackie G A

Abstract excerpt

Processing of 9 S precursor RNA in Escherichia coli requires the endoribonuclease RNase E, which makes two cleavages to liberate p5, the immature form of 5 S rRNA. The contributions of primary and secondary structure to RNase E-mediated cleavage of 9 S RNA were investigated. The structure of the 5' domain of 9 S RNA was probed by partial ribonuclease digestion and chemical modification. Our structural analysis of...

Topics

Base Sequence
DNA Mutational Analysis
Endoribonucleases
Escherichia coli
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
RNA Precursors
RNA Processing, Post-Transcriptional
RNA, Antisense
RNA, Ribosomal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Ribosomal, 5S

Structure-Activity Relationship

Substrate Specificity

Source

Identifiers

PMID: 1474579
DOI: 10.1016/0022-2836(92)90316-c

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1474579-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural requirements for the processing of Escherichia coli 5 S ribosomal RNA by RNase E in vitro.PMID 1474579Read ↗

Ribonuclease E provides substrates for ribonuclease P-dependent processing of a polycistronic mRNA.Semantic proximity Read ↗

Initiation of tRNA maturation by RNase E is essential for cell viability in E. coli.Semantic proximity Read ↗

In vitro processing of Drosophila melanogaster 5 S ribosomal RNA. 3' end effects and requirement for internal domains of mature 5 S RNA.Semantic proximity Read ↗

Evidence for an RNA binding region in the Escherichia coli processing endoribonuclease RNase E.Semantic proximity Read ↗

Ribonuclease P processes polycistronic tRNA transcripts in Escherichia coli independent of ribonuclease E.Semantic proximity Read ↗

Maturation of precursor 10Sa RNA in Escherichia coli is a two-step process: the first reaction is catalyzed by RNase III in presence of Mn2+.Semantic proximity Read ↗

Role of precursor sequences in the ordered maturation of E. coli 23S ribosomal RNA.Semantic proximity Read ↗

RNase J is required for processing of a small number of RNAs in Rhodobacter sphaeroides.Semantic proximity Read ↗

Gateway role for rRNA precursors in ribosome assembly.Semantic proximity Read ↗

Minimal functional structure of Escherichia coli 4.5 S RNA required for binding to elongation factor G.Semantic proximity Read ↗

A high-resolution view of RNA endonuclease cleavage in Bacillus subtilis.Semantic proximity Read ↗

Processing of the seven valine tRNAs in Escherichia coli involves novel features of RNase P.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.