Article
Resistance to diet-induced obesity in mice with a single substituted chromosome.
Physiological genomics - 17 Sept 2008
Buchner David A, Burrage Lindsay C, Hill Annie E, Yazbek Soha N, O'Brien William E, Croniger Colleen M, Nadeau Joseph H
Abstract excerpt
Obesity and its comorbidities are taking an increasing toll on human health. Key pathways that were identified with single gene variants in humans and model organisms have led to improved understanding and treatment of rare cases of human obesity. However, similar progress remains elusive for the more common multifactorial cases of metabolic dysfunction and disease. A survey of mouse chromosome substitution...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.