The immunoglobulin heavy chain and disease association: application to pemphigus vulgaris.

doi:10.1007/BF00206963

Back to search

Article

The immunoglobulin heavy chain and disease association: application to pemphigus vulgaris.

Human genetics - 1 Dec 1994

Gibson W T, Walter M A, Ahmed A R, Alper C A, Cox D W

Abstract excerpt

Genes involved in the immune response are generally encoded from a complex cluster of gene segments. Studies of the association of diseases with such genes require well-defined genetic markers throughout the selected region. A set of 15 polymorphic loci that span 1500 kb of the immunoglobulin hea...

Topics

Alleles
Child
Female
Gene Deletion
Genotype
Haplotypes
Humans
Immunoglobulin Heavy Chains
Male
Pemphigus
Polymorphism, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.