Article
The immunoglobulin heavy chain and disease association: application to pemphigus vulgaris.
Human genetics - 1 Dec 1994
Gibson W T, Walter M A, Ahmed A R, Alper C A, Cox D W
Abstract excerpt
Genes involved in the immune response are generally encoded from a complex cluster of gene segments. Studies of the association of diseases with such genes require well-defined genetic markers throughout the selected region. A set of 15 polymorphic loci that span 1500 kb of the immunoglobulin heavy chain (IGH) complex, 8 in the variable (VH) region and 7 in the constant (CH) region, were selected for the study of...
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