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Article

Variability of the immunoglobulin heavy chain constant region locus: a population study.

Human genetics - 1 Mar 1995

Brusco A, Cariota U, Bottaro A, Boccazzi C, Plebani A, Ugazio A G, Galanello R, Guerra M G, Carbonara A O

Abstract excerpt

The Immunoglobulin Heavy chain Constant region (IGHC) locus is a multigene family composed of highly homologous segments often involved in unequal crossings over that lead to deleted and duplicated haplotypes. The frequencies of these haplotypes in 558 individuals from Lombardy, Veneto, Puglia and Sardinia were determined by Pulsed Field Gel Electrophoresis (PFGE), followed by Southern blotting with four IGHC...

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Source

Identifiers

PMID: 7868126
DOI: 10.1007/BF00225201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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