Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene.

doi:10.1038/372464a0

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Article

Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene.

Nature - 1 Dec 1994

Wang Z Q, Fung M R, Barlow D P, Wagner E F

Abstract excerpt

The receptor for insulin-like growth factor type 2, also known as the cation-independent mannose-6-phosphate receptor (Igf2/Mpr), is a multifunctional receptor thought to play a role in lysosomal targeting, cell growth and signal transduction. Igf2/Mpr has been mapped to the mouse Tme locus and s...

Topics

Alleles
Animals
Biological Transport
Cell Line
Embryonic and Fetal Development
Endocytosis
Female
Genomic Imprinting
Lysosomes
Male
Mice
Mice, Knockout
Phenotype
Receptor, IGF Type 2

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