Article
Activation of a vmp pseudogene in Borrella hermsii: an alternate mechanism of antigenic variation during relapsing fever
1 Jul 1994
Abstract excerpt
The relapsing fever agent, Borrelia hermsii, undergoes multiphasic antigenic variation to evade its host's immune response. A frequently observed switch is serotype 7 to 26. Unlike silent vmp genes previously characterized, the transcriptionally silent vmp26 sequence was a pseudogene in lacking a start codon. In serotype 7 the location of the silent vmp26 sequence just downstream of vmp7 on the expression...
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