Article
Surface Protein Variation by Expression Site Switching in the Relapsing Fever Agent Borrelia hermsii
1 Dec 2000
Abstract excerpt
Borrelia hermsii, an agent of relapsing fever, undergoes antigenic variation of serotype-specifying membrane proteins during mammalian infections. When B. hermsii is cultivated in broth medium, one serotype, 33, eventually predominates in the population. Serotype 33 has also been found to be dominant in ticks but not in mammalian hosts. We investigated the biology and genetics of two independently derived clonal...
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