[The role of genetic and immunological factors in the etiology of insulin-dependent diabetes].

Article

[The role of genetic and immunological factors in the etiology of insulin-dependent diabetes].

Schweizerische medizinische Wochenschrift - 20 Jan 1990

Deschamps I, Hors J, Robert J J

Abstract excerpt

The mechanism of pancreatic B-cell destruction in type I (insulin-dependent) diabetes (IDDM) involves autoimmune phenomena based on genetic predisposition. The mechanism of action of the susceptibility genes is probably related to the function of the HLA molecules in the immune response. The gene...

Topics

Autoimmune Diseases
Diabetes Mellitus, Type 1
Genetic Markers
Genetic Predisposition to Disease
HLA-DR Antigens
Humans
Islets of Langerhans

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