Intracellular localization of the herpes simplex virus type 1 major transcriptional regulatory protein, ICP4, is affected by ICP27.

doi:10.1128/JVI.69.1.49-59.1995

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Article

Intracellular localization of the herpes simplex virus type 1 major transcriptional regulatory protein, ICP4, is affected by ICP27.

Journal of virology - 1 Jan 1995

Zhu Z, Schaffer P A

Abstract excerpt

Infected-cell protein 4 (ICP4) is the major transcriptional activator of herpes simplex virus (HSV) gene expression during productive infection. ICP0 has broad transactivating activity for all classes of HSV genes as well as cellular genes and genes of heterologous viruses. Together, the transact...

Topics

Animals
Cell Nucleus
Chlorocebus aethiops
Herpesvirus 1, Human
Immediate-Early Proteins
Mutation
Transcription Factors
Transcription, Genetic
Transfection
Vero Cells
Viral Proteins

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