Article
Progress towards gene therapy for HIV infection.
Gene therapy - 1 Jan 1994
Yu M, Poeschla E, Wong-Staal F
Abstract excerpt
The retroviral life cycle and genetic plasticity of human immunodeficiency virus 1 (HIV-1) present unprecedented therapeutic challenges. Twelve years into the HIV epidemic, satisfactory treatment remains elusive. Our current understanding of AIDS pathogenesis calls for early intervention with antiviral agents. Although still in its infancy, human gene therapy holds considerable potential for the long-term...
Topics
- Clinical Protocols
- Gene Transfer Techniques
- Genetic Therapy
- Genetic Vectors
- HIV Infections
- HIV-1
- Hematopoietic Stem Cell Transplantation
- Humans
- Immunotherapy
- Mutation
- RNA, Antisense
- RNA, Catalytic