Article
The function of the hypusine-containing proteins of yeast and other eukaryotes is well conserved.
Molecular & general genetics : MGG - 28 Sept 1994
Magdolen V, Klier H, Wöhl T, Klink F, Hirt H, Hauber J, Lottspeich F
Abstract excerpt
The hypusine-containing protein (Hypp) is highly conserved in evolution, from man to archaebacteria, but is not found in eubacteria. Hypp is essential for the viability for yeast cells, where two forms are encoded by the genes HYP1 and HYP2. The hypusine-containing protein Hyp2p, encoded by the HYP2 gene in yeast, is present under both aerobic and anaerobic conditions, whereas Hyp1p synthesis is restricted to...
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