Article
Characterization of cultured human ovarian surface epithelial cells: phenotypic plasticity and premalignant changes.
Laboratory investigation; a journal of technical methods and pathology - 1 Oct 1994
Auersperg N, Maines-Bandiera S L, Dyck H G, Kruk P A
Abstract excerpt
BACKGROUND: The ovarian surface epithelium (OSE) is a modified mesothelium that gives rise to most human ovarian carcinomas. In culture, OSE cells tend to assume atypical morphologies that make it difficult to accurately identify normal OSE cells and to recognize pathologic changes. The present s...
Topics
- Cadherins
- Cell Line
- Cells, Cultured
- Collagen
- Endothelium, Vascular
- Epithelial Cells
- Epithelium
- Female
- Fibroblasts
- Fluorescent Antibody Technique
- Humans
- Immunohistochemistry
- Laminin
- Ovary
- Phenotype
- Precancerous Conditions
- Simian virus 40