Article
Serous borderline ovarian tumors in long-term culture: phenotypic and genotypic distinction from invasive ovarian carcinomas.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jan 2000
Woo M M M, Salamanca C M, Miller M, Symowicz J, Leung P C K, Oliveira C, Ehlen T G, Gilks C B, Huntsman D, Auersperg N
Abstract excerpt
Serous borderline ovarian tumors (SBOTs) are differentiated, slow growing, noninvasive, and have a better prognosis than their invasive counterparts, but recurrence and progression to invasive carcinomas are common, and unlike high-grade serous carcinomas, they tend to be nonresponsive to chemotherapy. However, due to a lack of culture systems and animal models, information about the properties of SBOT and their...
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