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Article

Effects of epidermal growth factor/hydrocortisone on the growth and differentiation of human ovarian surface epithelium.

Journal of the Society for Gynecologic Investigation - 1 May 2004

Salamanca Clara M, Maines-Bandiera Sarah L, Leung Peter C K, Hu Yu-Long, Auersperg Nelly

Abstract excerpt

OBJECTIVE: Ovarian surface epithelium (OSE), the precursor of the epithelial ovarian carcinomas, has limited growth potential in culture. Epidermal growth factor+hydrocortisone (EGF+HC) enhances its growth but induces epitheliomesenchymal transition (EMT). This study was undertaken to define the effects of EGF+HC and their reversibility, to optimize growth-promoting media, and to relate OSE phenotypes in vitro to...

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Source

Identifiers

PMID: 15120699
DOI: 10.1016/j.jsgi.2003.10.010

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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