Article
Autonomy of the epithelial phenotype in human ovarian surface epithelium: changes with neoplastic progression and with a family history of ovarian cancer.
International journal of cancer - 20 Dec 1996
Dyck H G, Hamilton T C, Godwin A K, Lynch H T, Maines-Bandiera S, Auersperg N
Abstract excerpt
Epithelial ovarian carcinomas originate in the ovarian surface epithelium (OSE). In culture, OSE undergoes epithelio-mesenchymal conversion, an event mimicking a wound response, while ovarian carcinomas retain complex epithelial characteristics. To define the onset of this increased epithelial au...
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