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Article

Regulation of Id2 gene expression by the type 1 IGF receptor and the insulin receptor substrate-1.

Endocrinology - 1 Dec 2001

Navarro M, Valentinis B, Belletti B, Romano G, Reiss K, Baserga R

Abstract excerpt

The Id family of helix-loop-helix proteins is known to be involved in the proliferation and differentiation of several types of cells. The type 1 IGF receptor (IGF-IR) induces either proliferation or differentiation in 32D cells, a murine hemopoietic cell line, depending on the availability of the appropriate substrates for the receptor. We have previously reported that the IGF-IR regulates the expression of the...

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PMID: 11713209
DOI: 10.1210/endo.142.12.8548

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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