Article
Expression and functional phenotype of mouse ERG K+ channels in the inner ear: potential role in K+ regulation in the inner ear.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 21 Sept 2005
Nie Liping, Gratton Michael Anne, Mu Karen J, Dinglasan Judilee N, Feng Weihong, Yamoah Ebenezer N
Abstract excerpt
An outcome of the intricate K+ regulation in the cochlear duct is the endocochlear potential (EP), approximately 80 mV, the "battery" that runs hair-cell transduction; however, the detailed molecular mechanisms for the generation of the EP remain unclear. We provide strong evidence indicating that the intermediate cells (ICs) of the stria vascularis (StV) express outward K+ current that rectifies inwardly at...
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