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Article

Estrogen-related receptor beta/NR3B2 controls epithelial cell fate and endolymph production by the stria vascularis.

Developmental cell - 1 Sept 2007

Chen Jichao, Nathans Jeremy

Abstract excerpt

In the mammalian inner ear, endolymph is produced and resorbed by a complex series of epithelia. We show here that estrogen-related receptor beta (ERR-beta; NR3B2), an orphan nuclear receptor, is specifically expressed in and controls the development of the endolymph-producing cells of the inner ear: the strial marginal cells in the cochlea and the vestibular dark cells in the ampulla and utricle. Nr3b2(-/-)...

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Identifiers

PMID: 17765677
DOI: 10.1016/j.devcel.2007.07.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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