Article
Diploidy of Drosophila imaginal cells is maintained by a transcriptional repressor encoded by escargot.
Genes & development - 1 Oct 1994
Fuse N, Hirose S, Hayashi S
Abstract excerpt
The Drosophila escargot (esg) gene encodes a C2-H2-type zinc finger protein that is expressed in the imaginal discs and histoblasts. In some esg mutants, the abdominal histoblasts become polyploid. It has therefore been suggested that the role of esg is to maintain diploidy of the imaginal cells....
Topics
- Animals
- Base Sequence
- DNA
- DNA Probes
- Diploidy
- Drosophila
- Genes, Insect
- Helix-Loop-Helix Motifs
- Molecular Sequence Data
- Mutation
- Phenotype
- Protein Binding
- Repressor Proteins
- Salivary Glands
- Transcription, Genetic
- Transcriptional Activation
- Zinc Fingers