Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diploidy of Drosophila imaginal cells is maintained by a transcriptional repressor encoded by escargot.

Genes & development - 1 Oct 1994

Fuse N, Hirose S, Hayashi S

Abstract excerpt

The Drosophila escargot (esg) gene encodes a C2-H2-type zinc finger protein that is expressed in the imaginal discs and histoblasts. In some esg mutants, the abdominal histoblasts become polyploid. It has therefore been suggested that the role of esg is to maintain diploidy of the imaginal cells. We show that esg encodes a DNA-binding protein with high affinity for G/ACAGGTG, the consensus-binding sequence for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA
Share to Drosophila

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Phenotype

Share to Protein Binding

Share to Transcription, Genetic

Source

Identifiers

PMID: 7958894
DOI: 10.1101/gad.8.19.2270

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diploidy of Drosophila imaginal cells is maintained by a transcriptional repressor encoded by escargot.PMID 7958894Read ↗

Control of imaginal cell development by the escargot gene of Drosophila.Semantic proximity Read ↗

extramacrochaetae, a negative regulator of sensory organ development in Drosophila, defines a new class of helix-loop-helix proteins.Semantic proximity Read ↗

The basic-helix-loop-helix domain of Drosophila lethal of scute protein is sufficient for proneural function and activates neurogenic genes.Semantic proximity Read ↗

The Drosophila gene escargot encodes a zinc finger motif found in snail-related genes.Semantic proximity Read ↗

The Drosophila extramacrochaetae locus, an antagonist of proneural genes that, like these genes, encodes a helix-loop-helix protein.Semantic proximity Read ↗

Escargot restricts niche cell to stem cell conversion in the Drosophila testis.Semantic proximity Read ↗

Determination of wing cell fate by the escargot and snail genes in Drosophila.Semantic proximity Read ↗

An endogenous Su(Hw) insulator separates the yellow gene from the Achaete-scute gene complex in Drosophila.Semantic proximity Read ↗

Transvection and silencing of the Scr homeotic gene of Drosophila melanogaster.Semantic proximity Read ↗

The genetics of the Drosophila achaete-scute gene complex: a historical appraisal.Semantic proximity Read ↗

Spatial regulation of proneural gene activity: auto- and cross-activation of achaete is antagonized by extramacrochaetae.Semantic proximity Read ↗

The complex tale of the achaete-scute complex: a paradigmatic case in the analysis of gene organization and function during development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.