Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetically engineered mouse models for studying inflammatory bowel disease.

The Journal of pathology - 1 Jan 2016

Mizoguchi Atsushi, Takeuchi Takahito, Himuro Hidetomo, Okada Toshiyuki, Mizoguchi Emiko

Abstract excerpt

Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory condition that is mediated by very complex mechanisms controlled by genetic, immune, and environmental factors. More than 74 kinds of genetically engineered mouse strains have been established since 1993 for studying IBD. Although mouse models cannot fully reflect human IBD, they have provided significant contributions for not only...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokines
Share to Disease Models, Animal
Share to Gene Targeting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Neoplasm

Share to Genetic Engineering

Share to Inflammatory Bowel Diseases

Share to Mice, Transgenic

Share to Neoplasm Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 26387641
DOI: 10.1002/path.4640
PMCID: PMC4689626

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetically engineered mouse models for studying inflammatory bowel disease.PMID 26387641Read ↗

Animal models of IBD: linkage to human disease.Semantic proximity Read ↗

Mouse models of intestinal inflammation as tools to understand the pathogenesis of inflammatory bowel diseaseSemantic proximity Read ↗

Targeting the complex interactions between microbiota, host epithelial and immune cells in inflammatory bowel disease.Semantic proximity Read ↗

Gene-targeted immunologic knockouts: new models of inflammatory bowel disease.Semantic proximity Read ↗

Generation and Phenotypic Analysis of the IL-10RAR104W/R104W Mouse Model.Semantic proximity Read ↗

Insights from mouse models of colitis.Semantic proximity Read ↗

Lessons from genetic models of inflammatory bowel disease.Semantic proximity Read ↗

Mouse models of colorectal cancerSemantic proximity Read ↗

Harnessing murine models of Crohn's disease ileitis to advance concepts of pathophysiology and treatment.Semantic proximity Read ↗

Transgenic animals in inflammatory disease models.Semantic proximity Read ↗

Colitis-associated colon cancer: Is it in your genes?Semantic proximity Read ↗

Environmental and Microbial Factors in Inflammatory Bowel Disease Model Establishment: A Review Partly through Mendelian RandomizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.