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Article

Stage-specific requirement for myosin II during Dictyostelium development.

Development (Cambridge, England) - 1 Sept 1994

Springer M L, Patterson B, Spudich J A

Abstract excerpt

Dictyostelium cells that lack a functional myosin II heavy chain are motile and are capable of aggregation, but fail to undergo further multicellular development. We have used a Dictyostelium mutant expressing a cold-sensitive myosin heavy chain to examine the requirement for myosin throughout the course of development. The loss of myosin function upon cooling is rapid and reversible. Temperature-shift...

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PMID: 7956839
DOI: 10.1242/dev.120.9.2651

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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