Article
A polymorphism of the angiotensinogen gene associated with variation in blood pressure in a genetic isolate.
Circulation - 1 Nov 1994
Hegele R A, Brunt J H, Connelly P W
Abstract excerpt
BACKGROUND: The Hutterite Brethren are a genetic isolate characterized by high indices of relatedness and a communal agrarian lifestyle. We hypothesized that variation of the angiotensinogen (AGT) and angiotensin-converting enzyme (ACE) genes would be associated with variation in resting blood pr...
Topics
- Adult
- Aged
- Alleles
- Angiotensinogen
- Blood Pressure
- Codon
- Female
- Gene Frequency
- Humans
- Hypertension
- Male
- Middle Aged
- Peptidyl-Dipeptidase A
- Polymorphism, Genetic
- Sex Factors