Article
A polymorphism of the paraoxonase gene associated with variation in plasma lipoproteins in a genetic isolate.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 1995
Hegele R A, Brunt J H, Connelly P W
Abstract excerpt
The Hutterite Brethren are a genetic isolate characterized by high indices of relatedness and a communal agrarian lifestyle. We hypothesized that variation of the paraoxonase (PON) gene that underlies the interindividual variation in plasma PON activity would be associated with variation in fasting plasma lipoprotein variables in this group. In 793 Hutterites, we measured plasma lipids, lipoproteins, and...
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