A polymorphism of the paraoxonase gene associated with variation in plasma lipoproteins in a genetic isolate.

doi:10.1161/01.atv.15.1.89

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Article

A polymorphism of the paraoxonase gene associated with variation in plasma lipoproteins in a genetic isolate.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 1995

Hegele R A, Brunt J H, Connelly P W

Abstract excerpt

The Hutterite Brethren are a genetic isolate characterized by high indices of relatedness and a communal agrarian lifestyle. We hypothesized that variation of the paraoxonase (PON) gene that underlies the interindividual variation in plasma PON activity would be associated with variation in fasti...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Analysis of Variance
Aryldialkylphosphatase
Canada
Esterases
Female
Genetics, Population
Humans
Lipoproteins
Male
Polymorphism, Genetic

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