Analysis of two variants of the angiotensinogen gene in essential hypertensive African-Americans.

doi:10.1093/ajh/7.7.651

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Article

Analysis of two variants of the angiotensinogen gene in essential hypertensive African-Americans.

American journal of hypertension - 1 Jul 1994

Rutledge D R, Browe C S, Kubilis P S, Ross E A

Abstract excerpt

Two mutations (T174M and M235T) in the angiotensinogen gene have been reported to be associated with hypertension. This study examines the frequency of these mutations among African-American hypertensive patients (n = 109). The allele frequency of the T174M mutation was 4.6% and the frequency of...

Topics

Adult
Aged
Alleles
Angiotensinogen
Base Sequence
Black People
Female
Gene Frequency
Genes
Genotype
Humans
Hypertension
Male
Middle Aged
Molecular Probes
Molecular Sequence Data
Mutation
Polymerase Chain Reaction

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