Article
Analysis of two variants of the angiotensinogen gene in essential hypertensive African-Americans.
American journal of hypertension - 1 Jul 1994
Rutledge D R, Browe C S, Kubilis P S, Ross E A
Abstract excerpt
Two mutations (T174M and M235T) in the angiotensinogen gene have been reported to be associated with hypertension. This study examines the frequency of these mutations among African-American hypertensive patients (n = 109). The allele frequency of the T174M mutation was 4.6% and the frequency of the M235T mutation was 86.7%. The genotypic frequencies agreed with the conditioned Hardy-Weinberg predictions based on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.