Article
Association of angiotensinogen haplotypes with angiotensinogen levels but not with blood pressure or coronary artery disease: the Ludwigshafen Risk and Cardiovascular Health Study.
Journal of molecular medicine (Berlin, Germany) - 1 Mar 2005
Renner Wilfried, Nauck Markus, Winkelmann Bernhard R, Hoffmann Michael M, Scharnagl Hubert, Mayer Volker, Boehm Bernhard O, März Winfried
Abstract excerpt
Angiotensinogen and its cleaved forms angiotensin I and angiotensin II are important regulators of blood pressure. The gene for angiotensinogen (AGT) carries two common polymorphisms, T207M and M268T (previously described as T174M and M235T). To investigate the role of haplotypes formed by these polymorphisms for angiotensinogen levels we examined blood pressure, coronary artery disease (CAD), myocardial...
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